What Is Hepatitis C Antibodies (Anti-HCV)?
What it is
Anti-HCV antibodies indicate exposure to the hepatitis C virus — current or past infection.
Why it matters
A positive anti-HCV does not confirm active infection; HCV RNA testing is required to confirm.
Specimen
Whole blood / serum / plasma
Interpretation
Reactive = HCV antibodies detected (exposure). Non-reactive = not detected.
Limitations
Anti-HCV indicates exposure, not active infection — confirm with HCV RNA.
Related test: HCV Rapid Test — specimen: WB / S / P
Last reviewed: 2026-09-12